Sunday, January 30, 2011
Thursday, January 27, 2011
Tuesday, January 25, 2011
Sunday, January 23, 2011
Finally I will get to know what is like to live on Tatooine-homeplanet of Starwars hero Luke Skywalker. Or what it is like to live in a Arthur C. Clarke book- considering Jupiter turned into a second sun in the book 2010. Once at a "departmen
Saturday, January 22, 2011
Thank you Walt Disney for giving me inspiration to the headline.
Lets’s continue the Arsenic theme. Readers of Agatha Christie know arsenic to be a poison that kills. But what is arsenic? And how has it attracted worldwide interest because of its anticancer activity?
Chemically; It is the chemical element As. It has number 33 in the periodic table. Three metalloidal forms of arsenic, each with a different crystal structure and colour, are found free in nature. The name refers to yellow, which is one of colours that natrually occuring arsenic has.
Usage; beauty and poison/insecticide.
In the Victorian era, "white arsenic" trioxide was mixed with vinegar and chalk and eaten by women to improve the complexion, making their skin paler -indicating that they did not work in the fields. Arsenic was also rubbed onto the faces and arms of women to "improve their complexion". Women are thought to have died because of their cosmetic use. And we think plastic surgery and using hemorrhoid cream seems like an extreme idea.
Besides the it’s great addition to the old beauty industry, arsenic is an effective poison. If you want to now how arsenic kills, please look at the previous posting.
Recently it was shown that arsenic specifically kills leukemia cells. As has attracted worldwide interest because it shows substantial anticancer activity in patients with acute promyelocytic leukemia (APL). It is cancer of the blood and marrow. There is a constant turnover of cells in these tissues, and somewhere the cells that should end up as a specific granulocyte –a cell that fights infections- stop halfway and accumulate as “nonmature” granulocytes. Like a nursery where the children would never get old and move on to go to school and new children would continue to be accepted.
Arsenic trioxide (As2O3) exerts its therapeutic effect by promoting degradation of an oncogenic protein that drives the growth of APL cells, PML-RAR (a fusion protein containing sequences from the PML zinc finger protein and retinoic acid receptor alpha, I will write about these things in a later posting).
Chemical info about Arsenic; http://www.lenntech.com/periodic/elements/as.htm
About promyleocytic leukemia;
About the PML protein;
Friday, January 21, 2011
Have you ever wondered where all this water come from? The planet is filled with water, from the oceans that cover 70% of her surface to all life-forms that exist on this planet. Water is a common thread through all life. Life-forms does not necessarily need light or oxygen in order to survive, but no life-form can exist without water molecules. Our bodies does contain approximately 70% of water, just like the planet we have emerged from.
Water played a very important part in the evolution of life, being the major component of the primordial soup. Our reproductive cycle is a remembrance of the hydrolytic period in our own life.
But where did water molecules come from? Cause they were not a part of the planet when it formed? One theory is that the water came from outer space, from meteors with large icebodies that have crashed onto the planet. But how is water created from the beginning?
Scientists have now discovered that water molecules are created in interstellar dust in deep space. Each grain of interstellar dust provides a reactive surface on which wayward hydrogen and oxygen can combine into H2O. Eventually the two elements form an icy coating on the grain, the grains in the cloud condense gravitationally.
Suddenly having a glas of water became much more exciting.